Integrin alpha 3 Antibody

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NSJ Bioreagents
Product Code: NSJ-R30702
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30702-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Integrin alpha 3 antibody and Lane 1: rat heart; 2: HeLa cell lysate. Expected molecular weight: 119-150 kDa depending on glycosylation level.
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IHC-P: Integrin alpha 3 antibody testing of human intestinal cancer tissue
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IHC-P: Integrin alpha 3 antibody testing of rat brain tissue
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Western blot testing of Integrin alpha 3 antibody and Lane 1: rat heart; 2: HeLa cell lysate. Expected molecular weight: 119-150 kDa depending on glycosylation level.
IHC-P: Integrin alpha 3 antibody testing of human intestinal cancer tissue
IHC-P: Integrin alpha 3 antibody testing of rat brain tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ITGA3 (Integrin alpha 3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. It is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of the human protein increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, two potential cleavage sites, and the the N-terminal repeating units characteristic of ITGAs.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human ITG3A (LFGYSVALHRQTERQQR) was used as the immunogen for this Integrin alpha 3 antibody (100% homologous in human, mouse and rat).
Limitation:
This Integrin alpha 3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P26006