NSJ Bioreagents

Kallikrein-1 Antibody

Product Code:
 
NSJ-R30716
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Kallikrein-1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of Kallikrein-1 antibody and Lane 1: rat pancreas; 2: rat kidney~
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IHC-P: Kallikrein-1 antibody testing of rat kidney tissue
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Western blot testing of Kallikrein-1 antibody and Lane 1: rat pancreas; 2: rat kidney~
IHC-P: Kallikrein-1 antibody testing of rat kidney tissue

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CodeSizePrice
NSJ-R30716-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Kallikrein-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Kallikrein-1, also called KLKR, is a protein that in humans is encoded by the KLK1 gene. It is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of rat Kallikrein-1 (YTKLIKFTPWIKEVMKENP) was used as the immunogen for this Kallikrein-1 antibody.
Limitation:
This Kallikrein-1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Rat
Uniprot #:
P00758