KIM-1 Antibody

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NSJ Bioreagents
Product Code: NSJ-R30706
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30706-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the KIM-1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of KIM-1 antibody and Lane 1: SMMC-7721; 2: HeLa; 3: PANC; 4: M231; 5: M453 cell lysate. Predicted size: 40~50KD
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IHC-P: KIM-1 antibody testing of human tonsil tissue
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ICC testing of K562 cells
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Western blot testing of KIM-1 antibody and Lane 1: SMMC-7721; 2: HeLa; 3: PANC; 4: M231; 5: M453 cell lysate. Predicted size: 40~50KD
IHC-P: KIM-1 antibody testing of human tonsil tissue
ICC testing of K562 cells

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the KIM-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Kidney injury molecule 1, also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM-1 protein is a receptor for virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse KIM-1, it was found the protein expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM-1 during mouse T-cell differentiation leads to production of the Th2-type cytokine IL4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and the protein is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human KIM-1 (IKALQNAVEKEVQAEDN) was used as the immunogen for this KIM-1 antibody.
Limitation:
This KIM1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q96D42