Leupaxin Antibody

NSJ Bioreagents
Product Code: NSJ-R31317
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31317-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Leupaxin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Leupaxin antibody and Lane 1: rat thymus; 2: human Jurkat cell lysate. Expected/observed size ~43KD
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IHC-P: Leupaxin antibody testing of mouse spleen tissue
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IHC-P: Leupaxin antibody testing of rat spleen tissue

Western blot testing of Leupaxin antibody and Lane 1: rat thymus; 2: human Jurkat cell lysate. Expected/observed size ~43KD
IHC-P: Leupaxin antibody testing of mouse spleen tissue
IHC-P: Leupaxin antibody testing of rat spleen tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Leupaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, Leupaxin may also function in, and be regulated by, tyrosine kinase activity.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Leupaxin (KKHLPDKQDHKASLD) was used as the immunogen for this Leupaxin antibody.
Limitation:
This Leupaxin antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O60711