L-Selectin Antibody (CD62L)

Contact us
NSJ Bioreagents
Product Code: NSJ-R31964
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31964-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the CD62L antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

1 / 2
Western blot testing of 1) human placenta, 2) Jurkat, 3) CEM, 4) HL60, 5) rat spleen and 6) mouse spleen with CD62L antibody. Expected/observed molecular weight: 42~95 kDa depending on level of glycosylation.~
2 / 2
IHC testing of FFPE human tonsil with
❮❯

Western blot testing of 1) human placenta, 2) Jurkat, 3) CEM, 4) HL60, 5) rat spleen and 6) mouse spleen with CD62L antibody. Expected/observed molecular weight: 42~95 kDa depending on level of glycosylation.~
IHC testing of FFPE human tonsil with

Documents

Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,ELISA : 0.1-0.5ug/ml
Application Note:
Optimal dilution of the CD62L antibody should be determined by the researcher.
Description:
CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 39-372 of human CD62L were used as the immunogen for the CD62L antibody.
Limitation:
This CD62L antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P14151