MFN1 Antibody
| Code | Size | Price |
|---|
| NSJ-R31677-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the MFN1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the MFN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is a mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN?2, and to undergo ubiquitination by MARCH5. It has two key domains; One is a coiled?coil region that mediates MFN?1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression causes perinuclear mitochondrial clustering.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
55669
Immunogen:
An amino acid sequence from the N-terminal of human Mitofusin 1 (DQLLEFVTEGSHFVEATYKNPELDRIA) was used as the immunogen for this MFN1 antibody.
Limitation:
This MFN1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat