MMP12 Antibody

NSJ Bioreagents
Product Code: NSJ-R31265
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31265-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the MMP12 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of MMP12 antibody and Lane 1: human SMMC-7721; 2: mouse HEPA; 3: (h) HeLa; 4: (h) K562; 5: (h) MCF-7 cell lysate

Western blot testing of MMP12 antibody and Lane 1: human SMMC-7721; 2: mouse HEPA; 3: (h) HeLa; 4: (h) K562; 5: (h) MCF-7 cell lysate

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the MMP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Matrix metalloproteinase-12, also known as MME or ME, is an enzyme that in humans is encoded by the MMP12 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.2. It is though that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. This gene may involved in tissue injury and remodeling.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Matrix metalloproteinase-12 (KIDAVFYSKNKYYYFFQ) was used as the immunogen for this MMP12 antibody.
Limitation:
This MMP12 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P39900