MMP7 Antibody
| Code | Size | Price |
|---|
| NSJ-R31469-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
After reconstitution, the MMP7 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the MMP7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Matrix metalloproteinase-7, previously called putative metalloproteinase I (PUMP1) or Matrilysin has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The MMP7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, MMP7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. MMP7 is also a mediator of pulmonary fibrosis and a potential therapeutic target.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
17393
Immunogen:
Mouse partial recombinant protein (AA 95-264) was used as the immunogen for this MMP7 antibody.
Limitation:
This MMP7 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat