Monoamine Oxidase A Antibody

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NSJ Bioreagents
Product Code: NSJ-R30732
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30732-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Monoamine Oxidase A antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Monoamine Oxidase A antibody and human placenta lysate
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Western blot testing of 1) human RT4, 2) human placenta, 3) rat heart, 4) rat liver, 5) rat kidney and 6) mouse kidney lysate with Monoamine Oxidase A antibody. Predicted molecular weight: ~60 kDa.
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IHC-P: Monoamine Oxidase A antibody testing of human placenta tissue.
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Western blot testing of Monoamine Oxidase A antibody and human placenta lysate
Western blot testing of 1) human RT4, 2) human placenta, 3) rat heart, 4) rat liver, 5) rat kidney and 6) mouse kidney lysate with Monoamine Oxidase A antibody. Predicted molecular weight: ~60 kDa.
IHC-P: Monoamine Oxidase A antibody testing of human placenta tissue.

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Monoamine Oxidase A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Monoamine oxidase A is an enzyme that in humans is encoded by the MAOA gene. It is an isozyme of monoamine oxidase which is also mapped on Xp11.3. MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAOA levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Inhibition of the protein prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Monoamine Oxidase A (RTYTIRNEHVDYVDVGGAY) was used as the immunogen for this Monoamine Oxidase A antibody.
Limitation:
This Monoamine Oxidase A antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P21397