Monoamine Oxidase B Antibody

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NSJ Bioreagents
Product Code: NSJ-R30733
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30733-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the Monoamine Oxidase B antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Monoamine Oxidase B antibody and Lane 1: mouse liver; 2: (m) lung; 3: rat kidney; 4: (r) brain; 5: (r) liver; 6: (r) lung tissue lysate~
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IHC-P: Monoamine Oxidase B antibody testing of rat liver tissue
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Western blot testing of Monoamine Oxidase B antibody and Lane 1: mouse liver; 2: (m) lung; 3: rat kidney; 4: (r) brain; 5: (r) liver; 6: (r) lung tissue lysate~
IHC-P: Monoamine Oxidase B antibody testing of rat liver tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Monoamine Oxidase B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Monoamine oxidase B is a protein that in humans is encoded by the MAOB gene. It is a member of the flavin monoamine oxidase family. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAOB is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAOB inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of mouse Monoamine Oxidase B (RTYTIRNKNVKYVDL) was used as the immunogen for this Monoamine Oxidase B antibody (100% rat homology).
Limitation:
This Monoamine Oxidase B antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat
Uniprot #:
Q8BW75