MUC5AC Antibody / Mucin-5AC

NSJ Bioreagents
Product Code: NSJ-R31699
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31699-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the MUC5AC antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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IHC staining of FFPE rat stomach tissue with MUC5AC antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
2 / 2
IHC staining of FFPE human gastric carcinoma tissue with MUC5AC antibody. HIER: boil tissue sections

IHC staining of FFPE rat stomach tissue with MUC5AC antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.~
IHC staining of FFPE human gastric carcinoma tissue with MUC5AC antibody. HIER: boil tissue sections

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. It is also a direct and critical mediator of resistance during intestinal nematode infection.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
4586
Immunogen:
Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody.
Limitation:
This MUC5AC antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human