NALP3 Antibody (NLRP3)
| Code | Size | Price |
|---|
| NSJ-R31539-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the NALP3 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml
Application Note:
Titration of the NALP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
NLR Family, Pyrin domain containing 3, also known as CIAS1, CRYOPYRIN, NALP3 or PYPAF1, is a protein that in humans is encoded by the NLRP3 gene. It is mapped to 1q44. The encoded protein may play a role in the regulation of inflammation and apoptosis. Consistent with an essential role for NALP3 inflammasomes in antifungal immunity, it has been showed that deficient mice are hypersusceptible to C. albicans infection. Activation of the NLRP3 inflammasome in response to virus or to RNA was dependent upon lysosomal maturation and reactive oxygen species production in human cells. The inflammasome senses obesity-associated danger signals and contributes to obesity-induced inflammation and insulin resistance.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
114548
Immunogen:
Human partial recombinant protein (21-194) was used as the immunogen for this NLRP3 / NALP3 antibody.
Limitation:
This NALP3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human