Notch1 Antibody

NSJ Bioreagents
Product Code: NSJ-R30316
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30316-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
After reconstitution, the Notch1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of Notch1 antibody and Lane 1: MCF-7; 2: HeLa; 3: Jurkat; 4: COLO320. Predicted molecular weight: ~ 270 kDa (full length), ~ 120 kDa (transmembrane fragment).

Western blot testing of Notch1 antibody and Lane 1: MCF-7; 2: HeLa; 3: Jurkat; 4: COLO320. Predicted molecular weight: ~ 270 kDa (full length), ~ 120 kDa (transmembrane fragment).

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Notch1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated(NOTCH1), is a human gene encoding a single-pass transmembrane receptor. It functions as a receptor for membrane bound ligands, and may play multiple roles during development. NOTCH1 may normally coordinates the process of somitogenesis, and the activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the middle region of human Notch1 (QHSYSSPVDNTPSHQLQVPE) was used as the immunogen for this Notch1 antibody.
Limitation:
This Notch1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P46531