NRG1 Antibody

NSJ Bioreagents
Product Code: NSJ-R31075
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31075-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the NRG1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of NRG1 antibody and Lane 1: rat spleen; 2: (r) kidney; 3: (r) brain; 4: human HeLa; 5: (h) SMMC-7721 cell lysate
2 / 5
IHC-P: NRG1 antibody testing of human intestinal cancer tissue. HIER: steamed with pH6 citrate buffer.
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ICC testing of NRG1 antibody and HeLa cells
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IHC-P: NRG1 antibody testing of rat intestine tissue. HIER: steamed with pH6 citrate buffer.
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IHC-F testing of NRG1 antibody and rat intestine tissue

Western blot testing of NRG1 antibody and Lane 1: rat spleen; 2: (r) kidney; 3: (r) brain; 4: human HeLa; 5: (h) SMMC-7721 cell lysate
IHC-P: NRG1 antibody testing of human intestinal cancer tissue. HIER: steamed with pH6 citrate buffer.
ICC testing of NRG1 antibody and HeLa cells
IHC-P: NRG1 antibody testing of rat intestine tissue. HIER: steamed with pH6 citrate buffer.
IHC-F testing of NRG1 antibody and rat intestine tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the NRG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Neuregulin 1, also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. It is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NRG1 expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Neuregulin 1 (RFSTQEEIQARLSSVIANQD) was used as the immunogen for this NRG1 antibody.
Limitation:
This NRG1 antibody is available for research use only.
Localization:
Cytoplasmic, can be nuclear and membrane
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q02297