NRG2 Antibody

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NSJ Bioreagents
Product Code: NSJ-R30720
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R30720-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the NRG2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of NRG2 antibody and Lane 1: rat liver; 2: human COLO320; 3: SMMC-7721; 4: SW620 cell lysate. Predicted size: ~90KD
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Western blot testing of NRG2 antibody and Lane 1: rat liver; 2: human COLO320; 3: SMMC-7721; 4: SW620 cell lysate. Predicted size: ~90KD

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Neuregulin 2, also known as DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2 is a member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The genomic structure is similar to that of neuregulin 1(NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the middle region of human NRG2 (NGRKNSRLQFNKVKVEDA) was used as the immunogen for this NRG2 antibody.
Limitation:
This NRG2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O14511