P2X4 Antibody

NSJ Bioreagents
Product Code: NSJ-R31717
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31717-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
The P2X4 antibody can be stored at 40 to -200. After reconstitution, aliquot and store at -200. Avoid repeated freeze/thaws.

Images

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Western blot testing of 1) human HeLa, 2) human MCF7, 3) human A375, 4) human T-47D, 5) human A549, 6) monkey COS-7, 7) rat NRK, 8) rat RH-35, 9) mouse kidney, 10) mouse liver, 11) mouse RAW264.7 and 12) mouse HEPA1-6 cell lysate with P2X4 antibody. Expected molecular weight: 43-70 kDa depending on glycosylation

Western blot testing of 1) human HeLa, 2) human MCF7, 3) human A375, 4) human T-47D, 5) human A549, 6) monkey COS-7, 7) rat NRK, 8) rat RH-35, 9) mouse kidney, 10) mouse liver, 11) mouse RAW264.7 and 12) mouse HEPA1-6 cell lysate with P2X4 antibody. Expected molecular weight: 43-70 kDa depending on glycosylation

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
Variations in secondary/substrate sensitivities and test protocols may require the P2X4 antibody to be titrated for optimal performance.
Description:
Purinoceptor P2X4, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene. This gene belongs to the family of purinoceptors for ATP. P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel. P2X4 in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals. P2X receptors have beeb implicated in the regulation of cardiac function, ATP-mediated cell death, synaptic strengthening, and activating of the inflammasome in response to injury.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
5025
Immunogen:
Human partial recombinant protein (AA 262-388) was used as the immunogen for this P2X4 antibody.
Limitation:
This P2X4 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat, Monkey