pan-Cadherin Antibody
| Code | Size | Price |
|---|
| NSJ-R30069-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: CH-19, aka PC-79
Regulatory Status: RUO
Target Species:
- Chicken (Gallus)
- Human
- Mouse
- Rabbit
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
After reconstitution, the pan-Cadherin antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 1-2ug/ml,IHC (Paraffin): 2-4ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the pan-Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Cadherins are calcium-dependent adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma.
Format :
Ascites
Formulation :
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Gene ID #:
999, 1000, 1111
Immunogen:
Amino acids 1-24 of chicken N-Cadherin were used as the immunogen for this pan-Cadherin antibody.
Limitation:
This pan-Cadherin antibody is available for research use only.
Purity:
Ascites
Species Reactivity :
Human, mouse, rat, rabbit, chicken, snake