PKC epsilon Antibody

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NSJ Bioreagents
Product Code: NSJ-R31733
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31733-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the PKC epsilon antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of PKC epsilon antibody and Lane 1: rat brain; 2: Mosue brain; 3: human MCF-7. Predicted/observed size ~84KD
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IHC-P: PKC epsilon antibody testing of mouse intestine tissue
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IHC-P: PKC epsilon antibody testing of rat intestine tissue
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Western blot testing of PKC epsilon antibody and Lane 1: rat brain; 2: Mosue brain; 3: human MCF-7. Predicted/observed size ~84KD
IHC-P: PKC epsilon antibody testing of mouse intestine tissue
IHC-P: PKC epsilon antibody testing of rat intestine tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the PKC epsilon antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Protein kinase C epsilon, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. It is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist. It plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli. Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis, thereby leading to cell survival.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
5581
Immunogen:
Human partial recombinant protein (AA 53-236) was used as the immunogen for this PKC epsilon antibody.
Limitation:
This PKC epsilon antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat