Plgf Antibody / Pgf / Placenta growth factor

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NSJ Bioreagents
Product Code: NSJ-R32889
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R32889-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the Plgf antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of 1) rat stomach, 2) rat liver, 3) mouse stomach, 4) mouse liver and 5) mouse HEPA1-6 lysate with Plgf antibody at 0.5ug/ml. Predicted molecular weight: ~19 kDa (unmodified), ~28 kDa (glycosylated).
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Western blot testing of 1) rat stomach, 2) rat liver, 3) mouse stomach, 4) mouse liver and 5) mouse HEPA1-6 lysate with Plgf antibody at 0.5ug/ml. Predicted molecular weight: ~19 kDa (unmodified), ~28 kDa (glycosylated).

Documents

Further Information

Application Details :
Western Blot: 0.5-1ug/ml,Direct ELISA (recombinant rat protein): 0.1-0.5ug/ml (BSA-free format available)
Application Note:
Optimal dilution of the Plgf antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Description:
Placenta growth factor (PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor (VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors (VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant rat protein corresponding to amino acids A24-L158 was used as the immunogen for the Plgf antibody.
Limitation:
This Plgf antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat
Uniprot #:
Q63434