PTH1R Antibody

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NSJ Bioreagents
Product Code: NSJ-R31247
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31247-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the PTH1R antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of PTH1R antibody and Lane 1: SKOV; 2: U20S; 3: HeLa; 4: SMMC-7721 cell lysate; Observed/expected size ~66KD~
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IHC-P: PTH1R antibody testing of human thyroid cancer tissue
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Western blot testing of PTH1R antibody and Lane 1: SKOV; 2: U20S; 3: HeLa; 4: SMMC-7721 cell lysate; Observed/expected size ~66KD~
IHC-P: PTH1R antibody testing of human thyroid cancer tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the PTH1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human Parathyroid Hormone Receptor 1 (KLRETNAGRCDTRQQYRKL) was used as the immunogen for this PTH1R antibody (100% homologous in human, mouse and rat).
Limitation:
This PTH1R antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q03431