RSK1 Antibody

NSJ Bioreagents
Product Code: NSJ-R31163
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31163-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the RSK1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of RSK1 antbody; Lane 1: MCF-7; 2: HeLa; 3: K562; 4: Jurkat; 5: SW620; 6: Raji cell lysate. Predicted/observed size 83~90KD~
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Western blot testing of RSK1 antbody and Lane 1: A431; 2: MCF-7; 3: HeLa. Predicted/observed size 83~

Western blot testing of RSK1 antbody; Lane 1: MCF-7; 2: HeLa; 3: K562; 4: Jurkat; 5: SW620; 6: Raji cell lysate. Predicted/observed size 83~90KD~
Western blot testing of RSK1 antbody and Lane 1: A431; 2: MCF-7; 3: HeLa. Predicted/observed size 83~

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the RSK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Ribosomal Protein S6 Kinase, 90-KD, 1, also called RSK1, is an enzyme that in humans is encoded by the RPS6KA1 gene. The RSK(ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(RSK). Homologs exist in several species. By analysis of somatic cell hybrids, Moller et al.(1994) mapped the gene to chromosome 3. Bonni et al.(1999) characterized the mechanism by which the RAS-MAPK signaling pathway mediates growth factor-dependent cell survival. Inoue et al.(2007) demonstrated that p90RSK, the kinase immediately downstream from Mos-MAPK, directly targets Erp1 for CSF arrest in Xenopus oocytes.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human RSK1 (ILAQRRVRKLPSTTL) was used as the immunogen for this RSK1 antibody (100% homologous in human, mouse and rat).
Limitation:
This RSK1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q15418