SIRT6 Antibody

NSJ Bioreagents
Product Code: NSJ-R31770
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31770-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the SIRT6 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of SIRT6 antibody and Lane 1: HeLa; 2: A549; 3: human placenta lysate
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IHC-P: SIRT6 antibody testing of human breast cancer tissue
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IHC-P: SIRT6 antibody testing of mouse heart tissue

Western blot testing of SIRT6 antibody and Lane 1: HeLa; 2: A549; 3: human placenta lysate
IHC-P: SIRT6 antibody testing of human breast cancer tissue
IHC-P: SIRT6 antibody testing of mouse heart tissue

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Sirtuin 6, also known as SIR2L6, is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT6 is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
51548
Immunogen:
Human partial recombinant protein (AA 14-180) was used as the immunogen for this SIRT6 antibody.
Limitation:
This SIRT6 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse