TIMP4 Antibody
| Code | Size | Price |
|---|
| NSJ-R30263-100ug | 100 ug | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
After reconstitution, the TIMP4 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the TIMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The tissue inhibitors of metalloproteinases(TIMPs) inhibit matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. Expressed TIMP4 inhibits MMPs in vitro. TIMP4 gene is mapped to chromosome 3p25. TIMP-4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human TIMP4 (RGHLPLRKEFVDIVQP) was used as the immunogen for this TIMP4 antibody.
Limitation:
This TIMP4 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q99727