TRAF2 Antibody

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NSJ Bioreagents
Product Code: NSJ-R31114
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31114-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
After reconstitution, the TRAF2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of TRAF2 antbody and recombinant human protein, 30.4KD with tag; Lane 1: 10ng; 2: 5ng; 3: 2.5ng
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IHC-P: TRAF2 antibody testing of human tonsil tissue. HIER: steamed with pH6 citrate buffer.
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ICC testing of TRAF2 antbody and HeLa cells
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Western blot testing of TRAF2 antbody and recombinant human protein, 30.4KD with tag; Lane 1: 10ng; 2: 5ng; 3: 2.5ng
IHC-P: TRAF2 antibody testing of human tonsil tissue. HIER: steamed with pH6 citrate buffer.
ICC testing of TRAF2 antbody and HeLa cells

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the TRAF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
TNF Receptor-Associated Factor 2, also called TRAP, is a protein that in humans is encoded by the TRAF2 gene. The protein encoded by this gene is a member of the TNF receptor(TNFR) associated factor(TRAF) protein family. It is a common signal transducer for TNFR2 and CD40 that mediates activation of NF-kappa-B. Rothe et al.(1996) identified ITRAF, which binds to TRAF1, TRAF2, and TRAF3, and that when overexpressed inhibits TRAF2-mediated NF-kappa-B activation. They proposed that ITRAF is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Kanamori et al.(2002) found that mouse Traf2 interacted directly with T2bp, and they presented evidence that T2BP is involved in TNF-mediated signaling by its interaction with TRAF2.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the middle region of human TNF Receptor-Associated Factor 2 (RQHRLDQDKIEALSSKVQQLE) was used as the immunogen for this TRAF2 antibody.
Limitation:
This TRAF2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q12933