TSC2 Antibody

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NSJ Bioreagents
Product Code: NSJ-R31543
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31543-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
The lyophilized TSC2 antibody can be stored at 40 to -200. After reconstitution, aliquot and store at -200. Avoid repeated freeze/thaws.

Images

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Western blot testing of TSC2 antibody and human samples 1: U20S; 2: PANC; 3: HEPG2; 4: A549; 5: COLO320. Expected/observed size 200~220KD
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Western blot testing of TSC2 antibody and recombinant human protein (0.5ng)
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IHC-P: TSC2 antibody testing of human breast cancer tissue
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IHC-P: TSC2 antibody testing of mouse brain tissue
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IHC-P: TSC2 antibody testing of rat brain tissue
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Western blot testing of TSC2 antibody and human samples 1: U20S; 2: PANC; 3: HEPG2; 4: A549; 5: COLO320. Expected/observed size 200~220KD
Western blot testing of TSC2 antibody and recombinant human protein (0.5ng)
IHC-P: TSC2 antibody testing of human breast cancer tissue
IHC-P: TSC2 antibody testing of mouse brain tissue
IHC-P: TSC2 antibody testing of rat brain tissue

Documents

Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Tuberous sclerosis 2, also known as TSC2 or Tuberin is a protein that is in humans. Mutations in this gene lead to tuberous sclerosis complex. TSC2 is believed to be a tumor suppressor and is able to stimulate specific GTPases. It associates with hamartin in a cytosolic complex, possibly acting as a chaperone forHamartin. TSC2 is involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A andRAB5in vitro.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
7249
Immunogen:
Human partial recombinant protein (AA 1611-1807) was used as the immunogen for this TSC2 antibody.
Limitation:
This TSC2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat