UBC9 Antibody

NSJ Bioreagents
Product Code: NSJ-R31382
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-R31382-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
After reconstitution, the UBC9 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.

Images

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Western blot testing of UBC9 antibody and rat samples 1: heart; 2: skeletal muscle; 3: pancreas lysate. Predicted/expected size ~18KD

Western blot testing of UBC9 antibody and rat samples 1: heart; 2: skeletal muscle; 3: pancreas lysate. Predicted/expected size ~18KD

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the UBC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SUMO-conjugating enzyme UBC9, also called UBE2I, is a protein that in humans is encoded by the UBE2I gene. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2I could fully complement the mutant phenotype of a yeast ubc9 mutant strain. This gene may play a similar role via interaction with WT1, which is able to impose a block to cell cycle progression in eukaryotic cells. Additionally, it could support the growth of yeast ubc9 temperature-sensitive mutants at nonpermissive temperatures, indicating that the gene is a functional homolog of yeast ubc9. The protein is specifically associated with FHIT, such as FHIT may be involved in cell cycle control through its interaction with UBE2I.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human UBC9/UBE2I (IKQILLGIQELLNE) was used as the immunogen for this UBC9 antibody (100% homologous in human, mouse and rat).
Limitation:
This UBC9 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P63279