Welcome to ProSci - Distributed in the UK & Europe by Caltag Medsystems


ProSci Incorporated, a privately held biotech firm located in San Diego, California, offers a broad catalogue of over 30,000 research antibodies and over 20,000 completed Custom Antibody projects.

Their in-house labs and animal facilities (USDA licensed and NIH/OLAW approved) provide an extensive array of antibody services, with a focus on providing the highest quality of monoclonal, polyclonal, and single domain antibody services in the industry.

ProSci's expertise in antibody production, immunochemistry services, and biological research is realized through customizable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.

Established in 1998, ProSci is a reliable partner with over 20 years of serving the research community globally.

ProSci Products

ProSci specializes in the production of affinity-purified peptide-specific antibodies to novel antigens in fields such as HIV, Apoptosis, Signal Transduction, Neurobiology, Autophagy and Immunology. Please navigate through the filters under Products on the left-hand side column of this page to find ProSci products categorised by research area.

All ProSci polyclonal antibodies are affinity-purified, which allows for the isolation of antibodies specific to the epitope of interest. As a result, their polyclonal antibodies have the same specificity as monoclonal antibodies at a competitive price.

HIV research Antibodies

Their innovative approach to HIV research, using genetically engineered yeast strain and glycoproteins to mimic the HIV-1 glycan coat and to develop neutralizing antibodies against HIV-1 glycans has been awarded several Small Business Innovative Research (SBIR) grants by NIH. For all HIV-related antibodies please visit this page.

SARS-CoV-2 Antibodies

Furthermore, ProSci Incorporated is a leading contributor to the scientific research of SARS-Cov-2 by having antibody reagents available from the start of the pandemic outbreak. The use of the ProSci Spike Antibody (Cat. No. PSI-3525) has been cited in numerous publications in 2020 and 2021. Of great interest now, ProSci offers antibodies and recombinant proteins representing the full SARS-CoV-2 proteome, and host factors, including the availability of antibodies specific to emerging SARS-CoV-2 varients. To see all COVID-19 related products by ProSci, please go here.

Single Domain Antibodies

ProSci's Single Domain Antibodies products and services are highly valuable in fundamental research, diagnostic, and therapeutic applications. Single Domain Antibodies (sdAbs) from the camelid family are exciting and relatively new tools for researchers. These antibodies, also known as VHH antibodies or nanobodies, are isolated from camelid heavy chain only antibodies and are comprised of only the variable domain. As such, they lack light chains, are smaller and more stable compared to conventional antibodies, yet possess fully functional antigen-binding capability. Due to their size (approximately 15 kDa) and their longer CDR3 region, a single domain antibody is adept at reaching otherwise inaccessible epitopes that may play a crucial role in the molecular mechanisms of disease. To see the single domain antibody available please visit this page.

In addition, ProSci offers a complete assortment of cell lysates, tissue lysates, peptides and recombinant proteins to complement the use of these antibodies.

To find the products offered by ProSci for different research areas please see:

Autophagy, Cancer, Cell Cycle, Chemokines and Cytokines, Homeostasis, Immunology, Infectious Disease, Membrane, Neurobiology, Obesity, Phospho-specific, RNA Binding, Signal Transduction, Stem Cell, Transcription.

ProSci Custom Antibody Services

High quality technical assistance, competitive pricing, and highly customizable projects qualify ProSci staff as experts in Custom Antibody development and production.

The value and convenience of ProSci's custom antibody production services are further advanced with a complete spectrum of available immunochemistry services. These include but are not limited to antigen design assistance, antibody characterization, peptide synthesis, protein conjugation, and Immunohistochemistry. Caltag Medsystems is here with you every step of the way to support your custom antibody project with ProSci.

To learn more about these services, please visit their FAQ page.

ProSci custom antibody services include:

ProSci Support

For further supporting ProSci information please visit prosci-inc.com

Or, view the following links:

Blog posts

Research Grade Biosimilar Antibodies from ProSci

Therapeutic antibodies dominate pipelines and top selling drugs at major pharmaceutical companies. They have proven to be valuable tools in the f…


Antibody Basics: Recombinant Antibodies - ProSci Inc

The three most common methods to develop recombinant antibodies include display systems, direct B-cell cloning, or the use of pre-existing hybridomas.


Bacterial vs. Mammalian Expression Systems - ProSci

Expressing recombinant antibodies can be done in all kinds of systems. Many different cell lines can be used for expressing antibodies, including ma…


What is an Immunogen? - Prosci

Immunogens and Carrier Proteins What is an immunogen? An immunogen is a specific type of antigen that is able to elicit an immune response. Antibo…


A Summary of ProSci’s Research on HIV - ProSci

ProSci’s roots lie in the research of the Human Immunodeficiency Virus and working to develop a neutralising vaccine against it. Below is an …


Antibody Basics: Selecting Antigens - ProSci

When selecting an antigen to use for your project, the considerations required can be overwhelming. ProSci wants your antibody project to run smoothl…


Why Are Antibodies Produced in the Body? - ProSci

Antibodies are produced in the body to serve 3 major purposes in the immune system: neutralisation, opsonisation, and complement protein activation.…


The Role of Monoclonal Antibodies & Biosimilars in Research - ProSci Inc.

With more than 800 Research Grade Biosimilar antibodies in ProSci’s catalogue, these unique tools are available for researchers worldwide. Explore…


What is a Pseudovirus? - ProSci Inc.

It has been two years since the outbreak of coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was…


Monkeypox Virus: A breakthrough in Scientific News - ProSci Inc

The monkeypox virus that has been reported in mainstream and scientific news is part of the Orthopoxvirus genus that closely resembles smallpox (vari…


Highly Contagious Influenza Virus - ProSci Inc.

As of May 2022, a highly contagious influenza virus continues to wreak havoc on domestic bird flocks across the United States. Millions of chickens a…


SARS-CoV-2 Antibodies from ProSci

To support the efforts of researchers worldwide in understanding and combating SARS-CoV-2, ProSci Inc has developed and manufactured COVID-19 (SARS-Co…


Applications for Single Domain Antibody

The single-domain antibodies (sdAb), lack light chains, yet possess unique characteristics providing researchers a myriad of options not readily avail…


Single Domain Antibodies from ProSci Inc

Introduction Features and Benefits of Single Domain Antibodies Single Domain Antibody Development and Production Services Off-the-shelf Sing…


CTLA-4 Immune Checkpoint

ProSci Inc. offers an extensive range of antibodies and supporting tools to research CTLA-4. Read more about their range below, or click a link to…


TIGIT Immune Checkpoint

ProSci Inc. offers an extensive range of antibodies and supporting tools to research TIGIT Immune Checkpoint. Read more about their range below, or cl…



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